Cytadren

Cytadren
Aminoglutethimide Cytadren (aminoglutethimide) is one of the most interesting compounds in the manufacturer's arsenal of accessories. This is really not very popular today, but one or two decades ago, it was considered the state of affairs, and was appreciated for bodybuilders, many of its properties. Let's first consider the primary use is that, in ANTI-ESTROGEN complex. is able to produce very significant (almost total) estrogen fight (1), and it is certainly of interest to athletes who use steroids, which are converted to estrogen. Unfortunately, in this fight, estrogens are not accompanied by an increase in other hormones (testosterone, LH, FSH, etc. ..) that many other anti-estrogenic compounds cause. Thus, Cytadren, will probably not be the first choice for any person to use post-cycle treatment. The case, which, in my opinion, distinguishes it from other auxiliary compounds currently in use today is its unique ability to inhibit the production of cortisol. Cortisol, as you recall, is a catabolic hormone, but also destroys the muscles. Cytadren prevents the conversion of cholesterol to Pregnenolone (2), and also prevents the effect of aromatase. Thus, Cytadren quite unique in how these skills and, of course, none of the AI I've seen, since nothing similar to the effect of cortisol. Medical Cytadren used to fight against breast cancer and / or Hyperadrenocorticism and only medication currently (as far as I know) that can be successfully used for the purposes of (1) (3). May it be the same anti-depressant properties (4) (5). During a cycle, it can be used both to lower levels of cortisol with intense training, and reduce the level of estrogen. Sounds almost perfect, right? This use will allow us to consider using Arimidex, Nolvadex, or a compound similar to the strict use of the cycle, when growth of the test, LH, FSH, and would be more appropriate ... Well, not quite perfect, as you will soon see. The first problem is that a (possibly) could lead to a lower level of androgens. Best we can hope is that it has little influence on circulating levels of androgens (1). The problem is that eventually your body, a smart cookie, who begin to find ways to compensate for the reduction of cortisol, or more, or the difficulty Cytadren effect. Great ... Although cortisol is not present in your body, your joints will болящий. Yes, I actually used this equipment (I have in the name of science!), And he has worked and I look more "hair" and smaller, but I remember well, it made me sleep . May this be related to its effects on the adrenal cortex, I do not know, but it is good guess. If you think Cytadren on the use for this purpose, I must tell you to forget. Three grams of vitamin C reduced by nearly Cytadren cortisol in AMS 1000, literature, I have seen in both, and vitamin C, not to do so by your adrenal response (7). Grams of vitamin C reduced the cortisol 1/3rd ultramarathon competitors (8) (these are the people who apparently do not have cars, so they are forced to run 90 km at the time). I can not justify taking Cytadren for a long period of time, reducing cortisol levels when the vitamin could do the same, lower prices, but also other benefits. Then, we take care of Cytadren in liver toxicity (3). This material is very stressful to the liver. I think we can use milk and fields, but we really want to risk, where the impact of cortisol on the short term and could reduce the level of circulating androgens? Maybe ... See, you can use this equipment (if any) in the last week, up to weights for food, where your circulating androgens are now completely replaced by the synthetic androgen, and you do not give your adrenal several chances to close and make you lethargic, I think May is useful. Taking 500mgs/day for the last week of preparation for competition can help in a dry place, the latter song, and the province, a growing array of production of cortisol over long enough to make a CD of your competitors. For athletes of the examination of this connection to their cycles, I think that this is not a viable option, if you think all other options. References: Preservation of the secretion of androgens to estrogen suppression with aminoglutethimide in the treatment of metastatic breast cancer. J Clin Invest. 65 March 1980 (3): 602? 612. Adrenocortical steroidogenesis and aminoglutethimide I. biomedical research. Biomedicine. May 1973, 18 (3) :185-91. The use of aminoglutethimide in the treatment of pituitary-dependent Hyperadrenocorticism dogs. J Small Anim Pract. 2002 Mar; 43 (3) :104-8. The treatment of depression with antiglucocorticoid drugs.Psychosom Med. 1999 Sep-Oct; 61 (5) :698-711. Neuroendocrine responses to inhibitors of steroid biosynthesis in patients with major depression resistant to antidepressant therapy.Can J Psychiatry. April 1998, 43 (3) :279-86. Metastatic breast cancer with aminoglutethimide.Cancer. 1981 Apr 15; 47 (8) :1954-8. In the randomized controlled trial of high doses of ascorbic acid to reduce blood pressure, cortisol and subjective responses to psychological stress. Psychopharmacology (Berl). January 2002, 159 (3) :319-24. Epub 2001 Nov 20. Mitigation of traffic growth and cortisol increase the response of acute phase proteins in vitamin C-supplemented ultramarathoners.Int J